[1] Novak Djokovic 6-7,6-3,6-3,6-2 Kei Nishikori [56] 2021-09-04 17:40
Stadium: Arthur Ashe Stadium Round: 25 Ground: Hardcourt outdoor
Head to Head
| OL 2020 - Herre | 2021/07/29 09:00 | Novak Djokovic v Kei Nishikori | 6-2,6-0 |
| US Open | 2018/09/07 22:50 | Kei Nishikori v Novak Djokovic | 3-6,4-6,2-6 |
| Wimbledon | 2018/07/11 12:00 | Novak Djokovic v Kei Nishikori | 6-3,3-6,6-2,6-2 |
| ATP - Rom | 2018/05/18 16:15 | Kei Nishikori v Novak Djokovic | 6-2,1-6,3-6 |
| ATP - Madrid | 2018/05/07 14:00 | Kei Nishikori v Novak Djokovic | 5-7,4-6 |
| ATP World Tour Finals | 2016/11/19 20:00 | Novak Djokovic v Kei Nishikori | 6-1,6-1 |
| ATP - Madrid | 2016/05/07 18:20 | Novak Djokovic v Kei Nishikori | 6-3,7-6 |
| ATP - Miami | 2016/04/03 17:00 | Novak Djokovic v Kei Nishikori | 6-3,6-3 |
Home History
| US Open | 2021/09/02 23:00 | Novak Djokovic v Tallon Griekspoor | 6-2,6-3,6-2 |
| US Open | 2021/08/31 23:00 | Novak Djokovic v Holger Rune | 6-1,6-7,6-2,6-1 |
| OL 2020 - Herre | 2021/07/31 06:00 | Novak Djokovic v Pablo Carreno Busta | 4-6,7-6,3-6 |
| OL 2020 - Herre | 2021/07/30 07:35 | Novak Djokovic v Alexander Zverev | 6-1,3-6,1-6 |
| OL 2020 - Herre | 2021/07/29 09:00 | Novak Djokovic v Kei Nishikori | 6-2,6-0 |
| OL 2020 - Herre | 2021/07/28 07:15 | Novak Djokovic v Alejandro Davidovich Fokina | 6-3,6-1 |
| OL 2020 - Herre | 2021/07/26 07:50 | Novak Djokovic v Jan-Lennard Struff | 6-4,6-3 |
| OL 2020 - Herre | 2021/07/24 06:35 | Novak Djokovic v Hugo Dellien | 6-2,6-2 |
Away History
| US Open | 2021/09/02 19:55 | Kei Nishikori v Mackenzie McDonald | 7-6,6-3,6-7,2-6,6-3 |
| US Open | 2021/08/31 15:00 | Salvatore Caruso v Kei Nishikori | 1-6,1-6,7-5,3-6 |
| ATP - Toronto | 2021/08/10 15:00 | Miomir Kecmanovic v Kei Nishikori | 4-6,7-6,2-6 |
| ATP - Washington | 2021/08/07 22:00 | Kei Nishikori v Mackenzie McDonald | 4-6,6-3,5-7 |
| ATP - Washington | 2021/08/06 23:00 | Lloyd Harris v Kei Nishikori | 3-6,5-7 |
| ATP - Washington | 2021/08/05 20:35 | Kei Nishikori v Cameron Norrie | 3-6,6-3,6-3 |
| ATP - Washington | 2021/08/04 21:40 | Alexander Bublik v Kei Nishikori | 2-6,5-7 |
| ATP - Washington | 2021/08/02 23:00 | Kei Nishikori v Sam Querrey | 6-4,6-3 |
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