[5] Nacional Asunción 3-1 Guairena FC [7] 2022-04-20 22:00
Stadium: Estadio Arsenio Erico Round: 11
Referee: Jose Mendez Home Manager: Carlos Bonet Caceres Away Manager: Troadio Daniel Duarte
Head to Head
| Copa Sudamericana | 2022/03/17 22:15 | Guairena FC v Nacional Asunción | D | 0-0 |
| Copa Sudamericana | 2022/03/10 22:15 | Nacional Asunción v Guairena FC | L | 0-1 |
| Paraguay - Division Profesional | 2021/11/08 23:30 | Guairena FC v Nacional Asunción | D | 0-0 |
| Paraguay - Division Profesional | 2021/08/20 23:30 | Nacional Asunción v Guairena FC | L | 0-2 |
| Paraguay - Division Profesional | 2021/04/30 22:00 | Nacional Asunción v Guairena FC | L | 1-3 |
| Paraguay - Division Profesional | 2021/03/01 21:30 | Guairena FC v Nacional Asunción | L | 1-0 |
| Paraguay - Division Profesional | 2020/11/22 21:30 | Nacional Asunción v Guairena FC | D | 0-0 |
| Paraguay - Division Profesional | 2020/08/07 20:00 | Guairena FC v Nacional Asunción | D | 0-0 |
Home History
| Paraguay - Division Profesional | 2022/04/16 23:45 | Guarani Asuncion v Nacional Asunción | W | 0-1 |
| Paraguay - Division Profesional | 2022/04/09 00:15 | Olimpia Asuncion v Nacional Asunción | W | 1-2 |
| Paraguay - Division Profesional | 2022/04/03 22:00 | Nacional Asunción v Sportivo Ameliano | W | 2-1 |
| Paraguay - Division Profesional | 2022/03/21 21:00 | Tacuary v Nacional Asunción | L | 2-1 |
| Copa Sudamericana | 2022/03/17 22:15 | Guairena FC v Nacional Asunción | D | 0-0 |
| Paraguay - Division Profesional | 2022/03/14 23:15 | Nacional Asunción v Libertad Asuncion | L | 0-3 |
| Copa Sudamericana | 2022/03/10 22:15 | Nacional Asunción v Guairena FC | L | 0-1 |
| Paraguay - Division Profesional | 2022/03/04 22:00 | General Caballero JLM v Nacional Asunción | W | 1-2 |
Away History
| Paraguay - Division Profesional | 2022/04/17 19:45 | Guairena FC v Sportivo Ameliano | W | 2-1 |
| Copa Sudamericana | 2022/04/15 00:30 | Internacional v Guairena FC | D | 1-1 |
| Paraguay - Division Profesional | 2022/04/11 00:15 | Tacuary v Guairena FC | W | 0-1 |
| Copa Sudamericana | 2022/04/08 00:30 | Guairena FC v Independiente Medellin | D | 3-3 |
| Paraguay - Division Profesional | 2022/04/02 22:00 | Guairena FC v Libertad Asuncion | L | 2-3 |
| Paraguay - Division Profesional | 2022/03/21 23:15 | General Caballero JLM v Guairena FC | W | 0-1 |
| Copa Sudamericana | 2022/03/17 22:15 | Guairena FC v Nacional Asunción | D | 0-0 |
| Paraguay - Division Profesional | 2022/03/14 21:00 | Guairena FC v 12 de Octubre | D | 0-0 |
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