BUF Bills 0-21 CAR Panthers 2022-08-26 23:00
Stadium: Bank of America Stadium
Home Manager: Matt Rhule Away Manager: Sean McDermott
Head to Head
| NFL | 2021/12/19 18:00 | CAR Panthers v BUF Bills | W | 14-31 |
| NFL - Førsæson | 2019/08/16 23:00 | BUF Bills v CAR Panthers | W | 27-14 |
| NFL - Førsæson | 2018/08/09 23:00 | CAR Panthers v BUF Bills | L | 28-23 |
| NFL | 2018/02/02 09:34 | BUF Bills v CAR Panthers | L | 19-25 |
| NFL | 2017/09/17 17:00 | BUF Bills v CAR Panthers | L | 3-9 |
Home History
| NFL - Førsæson | 2022/08/20 17:00 | DEN Broncos v BUF Bills | W | 15-42 |
| NFL - Førsæson | 2022/08/13 20:00 | IND Colts v BUF Bills | W | 24-27 |
| NFL | 2022/01/23 23:30 | BUF Bills v KC Chiefs | L | 36-42 |
| NFL | 2022/01/16 01:15 | NE Patriots v BUF Bills | W | 17-47 |
| NFL | 2022/01/09 21:25 | NY Jets v BUF Bills | W | 10-27 |
| NFL | 2022/01/02 18:00 | ATL Falcons v BUF Bills | W | 15-29 |
| NFL | 2021/12/26 18:00 | BUF Bills v NE Patriots | W | 33-21 |
| NFL | 2021/12/19 18:00 | CAR Panthers v BUF Bills | W | 14-31 |
Away History
| NFL - Førsæson | 2022/08/19 23:00 | CAR Panthers v NE Patriots | L | 10-20 |
| NFL - Førsæson | 2022/08/13 17:00 | CAR Panthers v WAS Commanders | W | 23-21 |
| NFL | 2022/01/09 21:25 | CAR Panthers v TB Buccaneers | L | 17-41 |
| NFL | 2022/01/02 21:25 | CAR Panthers v NO Saints | L | 10-18 |
| NFL | 2021/12/26 18:00 | TB Buccaneers v CAR Panthers | L | 32-6 |
| NFL | 2021/12/19 18:00 | CAR Panthers v BUF Bills | L | 14-31 |
| NFL | 2021/12/12 18:00 | ATL Falcons v CAR Panthers | L | 29-21 |
| NFL | 2021/11/28 18:00 | CAR Panthers v MIA Dolphins | L | 10-33 |
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