Stadium: Memorial Stadium (Terre Haute) Round: 1
Home Manager: Curt Mallory Away Manager: Bob Nielson
| NCAAF | 2018/10/27 19:00 | South Dakota v North Dakota State | L | 14-59 |
| NCAAF | 2018/10/20 22:00 | Youngstown State v South Dakota | L | 29-17 |
| NCAAF | 2018/10/13 23:00 | Northern Iowa v South Dakota | L | 42-28 |
| NCAAF | 2018/10/06 19:00 | Missouri St v South Dakota | W | 28-35 |
| NCAAF | 2018/09/29 23:00 | South Dakota v SO Illinois | W | 31-24 |
| NCAAF | 2018/09/16 00:00 | South Dakota v Weber State | L | 10-27 |
| NCAAF | 2018/09/08 19:00 | Northern Colorado v South Dakota | W | 28-43 |
| NCAAF | 2018/09/01 23:00 | South Dakota v Kansas State | L | 24-27 |
| NCAAF | 2018/10/27 18:00 | Youngstown State v Indiana State | W | 17-43 |
| NCAAF | 2018/10/20 19:00 | SO Illinois v Indiana State | W | 21-24 |
| NCAAF | 2018/10/13 18:00 | Missouri St v Indiana State | L | 29-26 |
| NCAAF | 2018/10/06 23:00 | Indiana State v South Dakota State | L | 51-54 |
| NCAAF | 2018/09/27 23:00 | Northern Iowa v Indiana State | L | 33-0 |
| NCAAF | 2018/09/15 23:00 | Indiana State v Eastern Illinois | W | 55-41 |
| NCAAF | 2018/09/08 23:00 | Indiana State v Louisville | L | 7-31 |
| NCAAF | 2018/08/30 23:00 | Indiana State v Quincy | W | 49-0 |