[22] Colchester 2-0 Southend [23] 2021-04-20 18:00
Stadium: JobServe Community Stadium Round: 43
Referee: Kevin Johnson Home Manager: Hayden Mullins Away Manager: Phil Brown
Head to Head
| England - League 2 | 2020/12/26 13:00 | Southend v Colchester | L | 2-0 |
| England - EFL Trophy | 2020/11/10 19:00 | Colchester v Southend | W | 6-1 |
| England - EFL Trophy | 2018/10/09 18:45 | Colchester v Southend | W | 2-0 |
| England - EFL Trophy | 2017/11/07 19:45 | Southend v Colchester | L | 2-0 |
| England - League 1 | 2016/02/06 15:00 | Southend v Colchester | L | 3-0 |
| England - League 1 | 2015/12/26 15:00 | Colchester v Southend | L | 0-2 |
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