Clemson 47-21 Louisville 2017-09-17 00:00
Stadium: L&N Federal Credit Union Stadium Round: 1
Head to Head
| NCAAF | 2016/10/02 00:00 | Louisville v Clemson | W | 36-42 |
| NCAAF | 2015/09/17 23:30 | Louisville v Clemson | W | 17-20 |
| NCAAF | 2014/10/11 19:30 | Clemson v Louisville | W | 23-17 |
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